American Economic Review
ISSN 0002-8282 (Print) | ISSN 1944-7981 (Online)
How Do Patents Affect Follow-On Innovation? Evidence from the Human Genome
American Economic Review
vol. 109,
no. 1, January 2019
(pp. 203–36)
(Complimentary)
Abstract
We investigate whether patents on human genes have affected follow-on scientific research and product development. Using administrative data on successful and unsuccessful patent applications submitted to the US Patent and Trademark Office, we link the exact gene sequences claimed in each application with data measuring follow-on scientific research and commercial investments. Using this data, we document novel evidence of selection into patenting: patented genes appear more valuable—prior to being patented—than non-patented genes. This evidence of selection motivates two quasi-experimental approaches, both of which suggest that on average gene patents have had no quantitatively important effect on follow-on innovation.Citation
Sampat, Bhaven, and Heidi L. Williams. 2019. "How Do Patents Affect Follow-On Innovation? Evidence from the Human Genome." American Economic Review 109 (1): 203–36. DOI: 10.1257/aer.20151398Additional Materials
JEL Classification
- I10 Health: General
- O31 Innovation and Invention: Processes and Incentives
- O34 Intellectual Property and Intellectual Capital