MODLER
This package, which has been in development since its inception in
1968, was originally designed for the econometric analysis of small
or large scale econometric models. It has expanded into other areas,
including data management, general statistical analysis, and
simulations. It also offers close integration with common desktop
applications. It is in use by organizations around the world, and it
is available in different "sizes" (i.e. the maximum number of
equations a version can handle).
http://www.modler.com/